It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil target Cyp2d6 and plaquenil Summary. Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Note based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. Background and objectives Hydroxychloroquine is widely used in patients with rheumatoid arthritis. However, large-scale studies examining the long-term effects of hydroxychloroquine on the development of kidney disease in patients with rheumatoid arthritis are lacking. We aimed to assess the long-term association of hydroxychloroquine use with the risk of developing CKD in this population. Aug 26, 2016 I have Lupus Nephritis and have had it for almost 12 years now. I strongly suggest you get tested for it because it sounds like that's what you may have, especially with protein in your urine. Better to be safe than sorry. I also take Plaquenil but it's stictly for my joints, all of my other medications are for my kidney function. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine and kidney function Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Hydroxychloroquine Use and Risk of CKD in Patients with. What happens if you just stop taking plaquenilWhat is a plaquenil eye examCarbamazepine with chloroquineHow does hydroxychloroquine cause retinopathy This may cause protein to leak into the urine, along with red blood cells. Sometimes a kidney biopsy is needed to establish the exact diagnosis and treatment. Treatment options may include corticosteroids and immunosuppressive drugs to prevent loss of kidney function. This information was first printed in The Moisture Seekers, SSF's patient Sjögren’s & Kidney Disease. Plaquenil side effects - kidney problems? - Symptoms - Life.. Hydroxychloroquine - Wikipedia. The research team studied 582 patients with disease duration no longer than 5 years at baseline; 506 were treated with hydroxychloroquine. Seventy-three patients developed renal damage — defined as diminished renal function, end-stage renal disease, or proteinuria lasting at least 6 months — after a mean disease duration of 5.5 years. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.