One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine for malaria prevention Plaquenil maculopathy photos Plasmodium falciparum chloroquine resistance transporter Trametinib hydroxychloroquine The classic lesion is described as a “bull’s eye” with relative hypo pigmentation surrounding a central area of hyper pigmentation, but this is a late finding and many time patients suffer from irreversible vision loss. The goal for Plaquenil Screening to detect toxicity early and stop the medication as soon as possible if present. The official peer-reviewed, scientific journal of the ASRS provides a trusted resource for the highest-quality research and clinical information. Plaquenil lowers your immune system’s ability to cause inflammation. This can help control symptoms like rashes, skin and mouth sores and joint pain. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil ophthalmology retina specialist 2018 Ask a Doctor Can Plaquenil damage my eyes? Chattanooga Times Free Press, Home - The American Society of Retina Specialists Sam-e hydroxychloroquinePlaquenil for raynaud'What can happen if i stop taking plaquenil Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Plaquenil Side Effects on Your Eyes and Vision. What Is Plaquenil? - American Academy of Ophthalmology. PowerPoint. Update on Plaquenil Testing. Safe dosing by general practitioners and hospital specialists is likely to reduce the incidence of hydroxychloroquine retinopathy in patients at risk 7. A useful aide memoir for these guidelines for hydroxychloroquine is the 5 × 5 rule ideally keep dosage 5 mg/kg/day and screen after five years of drug use. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area.