Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil cancer Chloroquine and proguanil dose Plaquenil dose based on weight Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Plaquenil and hypoglycemia? Has anyone experienced this side effect? Newly diagnosed with early RA, rheumatologist started me on 200mg Plaquenil 1x/day for first two weeks, going up to 2x/day after two weeks. She told me it's very safe and generally well tolerated. Then about a week after going up to the full dosage I woke up feeling shaky. Plaquenil ® hydroxychloroquine – New Warnings • On January 27, 2017, the FDA approved new updates to the. Warnings. section of the Plaquenil hydroxychloroquine drug label regarding cardiac effects, including cardiomyopathy and QT prolongation, and hypoglycemia. • Plaquenil is indicated for the treatment of uncomplicated malaria due to Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and hypoglycemia Hydroxychloroquine and hypoglycaemia Most people., Plaquenil and hypoglycemia? rheumatoid Hydroxychloroquine side effects skin Use hydroxychloroquine with caution in patients with hypoglycemia or diabetes mellitus. Hydroxychloroquine can cause severe, life-threatening hypoglycemia in patients treated with or without antidiabetic medications. Warn patients about the risk of hypoglycemia and the associated clinical signs and symptoms. Plaquenil hydroxychloroquine sulfate dose, indications.. Plaquenil hydroxychloroquine – New Warnings. Plaquenil/hydroxychloroquine and hypoglycemia" Lupus.. Hydroxychloroquine HCQ, a commonly used antimalarial drug in rheumatic diseases, has shown favorable metabolic effects on both glucose control and lipid profiles. We describe a case of a young woman with type 1 diabetes whose glycemic control was optimized. Suicidal behavior has been rarely reported in patients treated with PLAQUENIL. Hypoglycemia. PLAQUENIL has been shown to cause severe hypoglycemia including loss of consciousness that could be life threatening in patients treated with or without antidiabetic medications see DRUG INTERACTIONS and ADVERSE REACTIONS. Patients treated with. Here we described a non-diabetic patient with RA who developed hypoglycaemia under hydroxychloroquine HCQ treatment. We also discussed the possible mechanisms of hypoglycaemia due to HCQ. A 62-yr-old man was admitted to our hospital with symmetric polyarthritis and morning stiffness for more than 2 h in 2005.