I saw a GP about it (not my usual one) and they strongly suspect it is being caused by MTX but I have just spoken to the Rheumy nurse who thinks Hydroxy is the more likely suspect or it may be an autoimmune response so now I have to withhold all rheumy meds. It seems to improve when I am on steroids but only at higher doses. Thanks, Tamara I am on all sorts of meds including MTX and Hydroxy. Does hydroxychloroquine affect menstrual cycle How to reverse the side gastrointestinal side effects of plaquenil I've been on Plaquenil for 6 weeks. I developed a red, raised, welt rash that looked like zebra stripes after being in the sun for 10 minutes. It went away within 30 minutes but then my joints all flared up the next few days. Check with your doctor! Find information about common, infrequent and rare side effects of Plaquenil Oral. Plaquenil and Rashes - from FDA reports Summary Rashes is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil. I can't face the GP again, as I am sure I am one of the "heart-sink" patients! I have recently developed an itchy rash which only affects my cheeks and eyebrows and haven't a clue what's causing it, so I hope you get some helpful replies that might help me too! What does a plaquenil rash look like Hydroxychloroquine Plaquenil Side Effects & Dosage for., Common and Rare Side Effects for Plaquenil Oral Plaquenil causes leg weakness in psoriatic arthritisWhat does plaquenil do to the immune system Plaquenil is most often well-tolerated but, like with any drug, side effects are possible. Most people about 90% who take antimalarial medications experience no side effects. If common side effects do occur, they are usually minor and last only for a short period of time. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Will you have Rashes with Plaquenil - eHealthMe. Skin rash 68 pictures, causes, and treatments. Lupus is an autoimmune disease that causes fatigue, joint pain, joint stiffness, and a butterfly-shaped rash on the face. In addition, some people with lupus experience hair loss. Losing your hair. I broke out with a rash after being on it for a week. I was also on a mild muscle relaxer for about 3 weeks prior to plaquenil. I got off both then started back on plaquenil. No rash so I assumed it was the other med even though I was on it longer and before the plaquenil. Did not resume the other meds. If it continues to happen, I will look into switching to the real deal plaquenil. Right now, I do think the medication is helping me. It has been a long time since I have been able to twirl my wedding rings around on my fingers. My swelling is gone! I am still waking up with a little stiffness, but not bad and no pain like before.