Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine retinopathy and night vision Plaquenil sweets syndrome Naltrexone and plaquenil Plaquenil generic vs name brand Therefore, the new guidelines suggest using a person’s height as a dosing factor. By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. Ideal Body Weight for Calculating Hydroxychloroquine Dosage. The most important risk factor for hydroxychloroquine retinopathy is the daily dose of the drug. If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range /= 6.5 mg/kg/day. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil dosing by weight ACR Actual-weight hydroxychloroquine dosing works in SLE, up., Plaquenil Risk Calculators Plaquenil muscle toxicityCan plaquenil cause seizuresTaking plaquenil on misdiagnosisAcr plaquenil Standard dosing At first, 800 milligrams mg 4 tablets taken as a single dose. Then, 400 mg taken 6 hours, 24 hours, and 48 hours after the first dose. Weight-based dosing Dose is based on body weight and must be determined by your doctor. At first, 13 milligram mg per kilogram kg of body weight taken as a single dose. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Ideal Body Weight for Calculating Hydroxychloroquine Dosage.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily Plaquenil caused some weight loss for me when I was on a higher dose. Now that I am on 200 mg. per day, I don't notice that anymore. Prednisone, on the other hand, has caused both a gain/loss, depending on the dosage. I noticed a six pound gain with Benlysta happened pretty quickly. That might change now that I am off the Benlysta. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. For people who weigh less than 80 kg, a lower daily dose is prescribed, up to a maximum of 5 mg/kg of body weight.