While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "Hydrochloroquine (Plaquenil) has been a blessing for me. Is chloroquine safe in pregnancy Aao plaquenil guideline Hydroxychloroquine eye exam guidance ncbi Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Mar 24, 2011 Had headaches with the plaquenil so went to the sulfar and predisone. Sulfar was a waste of time and since I had a little help from the plaquenil he switched me back to that with pain meds for the headaches and body. Recently i went back for app. and plaquenil had stopped doing anything so he added the methotrexate to it. I did not want to take it. I do occasionally experience dry eyes and a little scalp itch but asserting that it's caused by Hydrochloroquine would be anecdotal at best. It took about 5 weeks to take effect but my RA is basically a non factor now. Plaquenil stopped working What is the correct way to discontinue use of plaquenil?, Hydroxychloroquine Plaquenil Chloroquine vs doxycycline Jan 11, 2012 Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. Within a week most of them said that their symptoms came back with a vengence. They pretty much all restarted the drug and said they would stay on it cause it was working. Let me tell you what weaning down from Plaquenil is like.. What next if plaquenil doesn't work?. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Call your doctor right away if you notice any of these side effects Blurred vision or changes in your vision. Convulsions, seizures, or other neurological symptoms these are very rare. Muscle aches or weakness. Nervousness or anxiety. Headaches. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Re Plaquenil not working anymore Lizzy, I took 400mg 200 twice a day for 16-18 months forget exact duration, then was reduced to 200 mg daily. But right from the start, I also needed NSAID's for pain.