It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. How long until hydroxychloroquine works Does plaquenil cause dry eyes Chloroquine phosphate brooklynella Optimal use of disease‐modifying antirheumatic drugs DMARDs in rheumatoid arthritis is vital if progression of disease is to be reduced. Methotrexate MTX and sulfasalazine SASP are widely used inexpensive DMARDs, recently often combined despite no firm evidence of benefit from previous studies. The effects of methotrexate and hydroxychloroquine combination therapy vs methotrexate monotherapy in early rheumatoid arthritis patients Lisa Schapink. Sint Maartenskliniek and Radboudumc, MTX–HCQ combination therapy—together with a DAS28-based treat-to-target treatment strategy—has been part of the early RA treatment protocol. A more chronic form of interstitial lung disease and fibrosis is also seen in patients with rheumatoid arthritis. This may be increased with methotrexate. Myelosuppression lowering of blood counts is also rare at the low doses of methotrexate utilized for rheumatoid arthritis. Patients at particular risk include those with renal insufficiency from other causes or use of trimethoprim Bactrim®, Septra® which increases levels of methotrexate. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and methotrexate together Plaquenil Oral Interactions with Other Medication, Effects of methotrexate and hydroxychloroquine combination. Chloroquin site drugs.comIs hydroxychloroquine an anti inflammatotyPlaquenil overdose treatmentPlaquenil and neurotransmitter acetylcholine Learn about drug interactions between hydroxychloroquine and methotrexate and use the RxList drug interaction checker to check drug combinations. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media Hydroxychloroquine and methotrexate Drug Interactions - RxList. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Plaquenil & other drug interactions ? Lupus Forums at.. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. I had a biopsy and my doctor said he believes it is morphea. I am waiting on my blood test to come back and he said as soon as it does he will put me on both methotrexate and doctor is a very good derm. Interaction between Methotrexate and Plaquenil There is no known interaction between Methotrexate and Plaquenil in our records. However, an interaction may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice.