It leads to fluid buildup, especially in your legs. Other symptoms of congestive heart failure: Deep vein thrombosis (DVT) and thrombophlebitis: If you have DVT, it means there's a blood clot in a vein in your leg. When that happens, it's called a pulmonary embolism, and it can be life-threatening. Plaquenil and weed Hydroxychloroquine and blood sugar Many people using this medication do not have serious side your doctor immediately if any of these unlikely but serious side effects occur arm/leg/back pain, fast heartbeat, hair loss/color change, mental/mood changes e.g. anxiety, depression, hallucinations, ringing in the ears/hearing loss, worsening of skin conditions e.g. psoriasismedication may infrequently cause serious sometimes permanent eye problems or muscle damage, especially if you take it for a long time. Plaquenil can cause edema in the feet and legs. One of the warnings says to contact your doctor if you develop swelling/edema in the feet and legs. I had a medication cause me to retain fluid and I gained 6.5 pounds in 2 days. All of it was in my legs and feet. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. One of the first symptoms of DVT or thrombophlebitis is one swollen leg (especially the calf), as blood pools in the area. In thrombophlebitis, also called superficial thrombophlebitis, clots form closer to the surface of the skin and aren't likely to break off. Plaquenil leg swelling How Lupus Affects the Muscles, Tendons and Joints Lupus., Please tell me about your swollen ankles/calves.there. Hydroxychloroquine 200 mg tab couponPepto bismol and plaquenilAre there consequences to not taking plaquenil Sep 13, 2019 Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Hydroxychloroquine Oral Route Description and Brand.. Taking Plaquenil for Rheumatoid Arthritis. Sep 13, 2019 large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs; loss of hearing; lower back or side pain; noisy breathing; painful or difficult urination; red irritated eyes; red skin lesions, often with a purple center; severe mood or mental changes; sore throat sores, ulcers, or white spots on the lips or in the mouth Nov 28, 2018 Heavy legs and edema in the ankles occur due to vascular insufficiency. Monitor your diet and eliminate salt when possible. This leads to swelling in the ankles and high-blood pressure. Keeping your legs above your heart helps maintain the flow of venous blood. Heavy legs and edema may be secondary to another illness such as diabetes. PLAQUENIL is a synthetic Quinilone, belongs in the Floro Quinilone family which has a black box warning by the FDA. I did not this at the time i took it. Previously had bad tendon damage with Cipro.