It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine in diabetes Plaquenil dosage mg kg INTRODUCTION Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Hydroxychloroquine is classified as an anti-malarial drug. It is similar to chloroquine Aralen and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis. Its mechanism of action is unknown. Malarial parasites invade human red blood cells. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine in sle Hydroxychloroquine - Wikipedia, PDF Hydroxychloroquine in systemic lupus erythematosus SLE Does plaquenil help osteoarthritisPlaquenil 200mg bidPlaquenil low doseChloroquine phopshate usp Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine in systemic lupus erythematosus results of a French.. Chloroquine and hydroxychloroquine are approved for the treatment of SLE and have been shown to reduce the frequency of disease flares particularly of lupus nephritis, contribute to the. Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and chloroquine in the treatment of rheumatoid arthritis RA, systemic lupus erythematosus SLE and other. Hydroxychloroquine is recommended for all patients with systemic lupus erythematosus to reduce disease activity and improve damage-free-survival,” Shivani Garg, MD, MS, of the University of.