I didn't seem to have any problems whatsoever with it initially, other than very short term and mild cramping/diarrhea. But now I've been dealing with considerable muscle aching and pain/spasm in some new places - or at least places that haven't bothered me in quite awhile. What can you expect when you stop taking plaquenil Plaquenil toxicity retina It is prescribed as a disease-modifier, in other words, to decrease pain and swelling, and prevent joint damage and disability. There is evidence that hydroxychloroquine may interfere with communication between cells in the immune system. Can stopping Plaquenil cause joint pain to return? Asked by kcd250 Updated 10 February 2012 Topics plaquenil, osteoarthritis, pain, sjogren's syndrome, systemic lupus erythematosus. I have been on plaquenil for about 3 years. At one time, i tried to stop taking it due to money issues. I started experiencing joint pain in my hips. Tell your doctor if you experience serious side effects of Plaquenil including. muscle weakness, twitching, uncontrolled movement, loss of balance or coordination, blurred vision, light sensitivity, seeing halos around lights, I felt the Plaquenil helped the fatigue, but it seems the pain is sabotaging that effect. My knees and legs hurt, back, hips, shoulders, fingers, and now my left heel - which has me limping half the time. Can plaquenil cause joint pain Plaquenil Side Effects Common, Severe, Long Term -, Can stopping Plaquenil cause joint pain to return? Chloroquine hallucinations robert baleActavis pharma plaquenilGluten free plaquenilCan plaquenil cause bone avascularPlaquenil and low white blood count Hate it. before my diagnosis I was tired,aneamic,stiff etc since the plaquenil I jus flare all the time. it was so bad I just came off it for several months. got so ill they wanted me to go on chemo based drugs but I did not want that either. so reluctantly went back on the plaquenil. imo its made me worse. When starting hydroxychloroquine do symptoms feel. - LUPUS UK. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias joint pain, dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can.