Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Joint pain after stopping plaquenil Hair loss plaquenil Plaquenil free Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia. Nerve problems or Porphyria blood disorder or Psoriasis skin disease or Stomach or bowel problems–Use with caution. May make these conditions worse. Glucose-6-phosphate dehydrogenase G6PD deficiency—May cause hemolytic anemia in patients with this condition. Kidney disease or Liver disease—Use with caution. For information and support call 0300 3030 111. Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Hydroxychloroquine and nerve damage Hydroxychloroquine Side Effects Common, Severe, Long Term., Hydroxychloroquine Oral Route Before Using - Mayo Clinic Tlr7 hydroxychloroquine ic50 Feb 19, 2020 Significant risk factors for retinal damage include daily doses of hydroxychloroquine sulfate greater than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate and concurrent macular disease. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Eye screening for patients taking hydroxychloroquine Plaquenil. Eye screening for patients taking hydroxychloroquine.. Hi Daisy. I have had Lupus for 12yearsthat I know about and have taken Hydroxy for 10yrs It has been very succesful at keeping my lupus from getting out of hand. About a year ago i had a similar problem and was sent to a specialist for nerve tests. Thankfully the results showed no nerve damage. But the problem still existed. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Topiramate Topamax is used to treat epilepsy and migraines. The drug also is used off-label for a number of concerns, including weight loss, bipolar disorder and depression. It has been associated with acute angle-closure glaucoma and transient myopia. Statins may be associated with diplopia.