It is the most common form of scarring hair loss seen in black women. Hair care practices, such as the use of the hot comb, relaxers, tight extensions and weaves, have been implicated for decades, but studies have not shown a consistent link. The goal of therapy is to halt progression of disease and prevent further hair loss. Chloroquine and osmotic lysis of endosome Is plaquenil a disease modifying May 17, 2017 The chance of helping for autoimmune especially scarring alopecias is high. Hydroxychloroquine does not help all hair loss types but does help conditions such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Hair loss from these drugs is not common. Mid‐frontal density increased improvement of associated female pattern hair loss, but there was increasing anterior hairline recession as a result of frontal fibrosing alopecia progression. After 12 months, daily ciclosporin 25 mg was initiated, and hydroxychloroquine was ceased. Dutasteride, minoxidil and spironolactone were continued. Lichen planopilaris LPP is a primary lymphocytic scarring alopecia that causes inflammation, erythema, pruritus, dysesthesia, and alopecia that can be treatment resistant. After approval from the institutional review board, we performed a retrospective case analysis of alopecia due to LPP to assess possible therapeutic effectiveness. As the exact cause is not known, should be treated with appropriate medicated shampoos and topical anti-inflammatory agents as needed. In areas where the hair follicle has been replaced with fibrosis, regrowth is not possible. Hydroxychloroquine scarring alopecia Frontal Fibrosing Alopecia - Dermatology Advisor, Frontal fibrosing alopecia Regrowth following cessation. Plaquenil for hair loss treatment Feb 26, 2018 A systematic approach to the evaluation of alopecia allows for more effective management. Below is a step-by-step approach that can be used in scarring alopecia Initial classification of alopecia type Applying scarring alopecia terminology based on clinical features Using histology findings to further support/define the diagnosis Providing a. Scarring Alopecia Clinical Presentation History, Physical.. Lichen Planopilaris Retrospective Study and Stepwise.. Causes and Treatment of Frontal Fibrosing Alopecia FFA. Most forms of primary cicatricial alopecia develop in early adult life. With the exception of 2 rare familial genodermatoses keratosis follicularis spinulosa decalvans and Marie Unna hypotrichosis, onset in childhood or adolescence is rare. 5,9 Frontal fibrosing alopecia occurs in postmenopausal women. Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. In the field of hair loss, conditions such as lichen planopilaris, frontal fibrosing alopecia and discoid lupus are frequently treated with hydroxychloroquine. Alopecia areata is a tissue restricted autoimmune disease directed at the hair follicle, resulting in hair loss. Patients frequently suffer severe psychiatric consequences. This is especially true of girls and young women who become bald. The incidence of alopecia areata in the USA.