It can be difficult to discern the difference between all the products available to you. Read our article below as we explain the active ingredients in each product and what they are used for. Hydroxychloroquine not working what next Hydroxychloroquine plaquenil drug class How to use Mucinex. Take this medication by mouth with or without food, as directed by your doctor, usually every 12 hours with a full glass of water. If you are self-treating, follow all directions on the product package. If you are uncertain about any of the information, ask your doctor or pharmacist. Mucinex D is a non-prescription combination medicine that's used to treat symptoms of the common cold, infections, or allergies. It contains the drugs guaifenesin an expectorant, which is also used in other medications marketed under the Mucinex brand, and pseudoephedrine a nasal decongestant. I am very happy and hope that I can stay on Plaquenil. I feel like I just might get my life back. Not like it was when I was younger, but much improved compared to my life for the past 10 years. I am seronegative and and oh so happy my Rheumy let me try Plaquenil. I take Plaquenil at bedtime, and have experienced that "rocking boat" effect too! Mucinex is used as an expectorant which helps to loosen and thin mucus as well as bronchial secretions. Guaifenesin Mucinex, the original product, contains one active ingredient, guaifenesin. Can i take mucinex d with plaquenil Plaquenil Drug and Medication User Reviews on RxList, Mucinex D Guaifenesin & Pseudoephedrine - Side Effects. Volume of distribution of chloroquine ANSWER Hi there, At first, I want to remind you that Mucinex is a drug used to relieve the cough. However, as any other drugs, Mucinex has side effects and precautions, to which you have to pay attention. Mucinex & Enlarged Prostate. Plaquenil and dizziness? Updated. Plaquenil and cold medicines DailyStrength. How to use Mucinex D Tablet, Extended Release 12 Hr. Take this medication by mouth with or without food, usually every 12 hours with a full glass of water or as directed by your doctor. If stomach upset occurs, take with food or milk. If you are self-treating, follow all directions on the product package. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Jan 22, 2016 Yes, you can do this. The active ingredient in Mucinex is guaifenesin. There is a DayQuil preparation called "Dayquil Mucus Control" that contains guaifenesin. In general, mucinex is safe to take with any other cold medicine that doesn't already contain guaifenesin.