The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities. 60 increase in malaria deaths after chloroquine failure Plaquenil weight based dosing Taking chloroquine in pregnancy Side effects of Plaquenil and Aralen that are similar include nausea, vomiting, stomach pain or cramps, diarrhea, headache, or hair loss. Side effects of Plaquenil that are different from Aralen include loss of appetite, weight loss, dizziness, spinning sensation, ringing in your ears, mood changes, nervousness, irritability, skin rash, or itching. Preventing Lupus Leg Cramps. Leg cramps can be caused by muscle strain or dehydration. If you are athletic, you should take precautions to ensure that you do not become dehydrated. Sometimes leg cramps are brought about because your extremities do not get an adequate blood supply when you are exercising. Lastly, there are some non-pharmacologic solutions to nighttime leg cramps 1 Walking or leg jiggling followed by leg elevation. 2 A hot shower with the stream directed at the cramp area of the body, usually for five minutes, or a warm tub bath. 3 Ice massage. Medications that are strongly associated with leg cramps include intravenous iron sucrose, conjugated estrogens, raloxifene, naproxen, and teriparatide. Nocturnal leg cramps are associated with vascular disease, lumbar canal stenosis, cirrhosis, hemodialysis, pregnancy, and other medical conditions. Plaquenil leg cramps Stomach problems with Plaquenil • Johns Hopkins Arthritis Center, Lupus Cramps Dr Garys Lupus Treatment System Cure & Relief How long for plaquenil rash to go awayPlaquenil toxicity in macular oct layer changesWho should not take plaquenil Apr 10, 2019 Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay. Plaquenil Uses, Dosage & Side Effects -. Nighttime Leg Cramps Meds That Hurt, Meds That Help - GoodRx. Plaquenil Prices, Coupons & Savings Tips - GoodRx. Hydroxychloroquine Plaquenil is commonly used for treating joint pain in Sjögren’s syndrome patients, based in part on its efficacy in treating the joint pain of patients with systemic lupus erythematosus and rheumatoid arthritis. Jul 18, 2008 I have been on 400 mg daily of Plaquenil, last week my doctor took me off of it ue to increase in the pain I had been having in lower back and unbelievable pain in my left leg and especially the extreme pain in the heel of my left foot. It was becoming painful to walk. After 5 days of stopping pain was 80% better. Plaquenil and Restless leg syndrome - from FDA reports Summary Restless leg syndrome is found among people who take Plaquenil, especially for people who are female, 40-49 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Osteoporosis.