It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Antimalarial hydroxychloroquine Plaquenil and c diff Can plaquenil affect your thyroid Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. How Long Does It Take for Medicine to Absorb? Credit Kristian Sekulic/E+/Getty Images According to About.com, how long medicine takes to absorb into the stomach depends on the type of medication, whether it is taken with food or on an empty stomach, and the ability of the medication to pass into the bloodstream. Mark a calendar to help you remember. This drug is usually started 2 weeks before entering the area with malaria. Take it once weekly while in the area, and continue taking it for 4 to 8 weeks after leaving the area or as directed by your doctor. To treat malaria, follow your doctor's instructions. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long will plaquenil stay in your system Plaquenil -, How Long Does It Take for Medicine to Absorb? Plaquenil pregnancy otisBest way to take plaquenil With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. May 05, 2016 Plaquenil seems to be a good baseline drug to start when first diagnosed with inflammatory connective tissue disease and one that many people will probably stay on for continued disease management. Nov 02, 2010 It takes around 5.5 half lives for a drug to be completely eliminated from your body meaning that you may need to wait for around 176 days. Further Information Hydroxychloroquine Drug Information Mar 07, 2012 In response to the original question, 60 to 90 days, as long as it take to become effective. As far as panic attacks and side effects are concerned, I have been on it for nine months and the first two weeks are less than comfortable nausea, change in taste, ringing in your ears, hot and cold flashes are completely typical.