Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and antiplatelet drugs Hydroxychloroquine sulfate adverse reactions Plaquenil and blood pressure One of the potential long-term side-effects of using anti-malarial medications such as hydroxychloroquine Plaquenil, chloroquine, and quinacrine is the development of dark-colored patches on the skin. They often appear brown, black, or black and blue and tend to develop on the legs, especially around the shins. What does hydroxychlorqoune hyperpigmentation look like? Skin pigmentation related to use of hydroxychloroquine starts out as a yellow brown to slate gray or black pigmentation on many areas of the body - especially the front of the shins but also the face, forearms, mouth mucosa essentially hard palace and gingivae and nail beds. Picture of Phytophotodermatitis Hyperpigmentation. Phytophotodermatitis plant light dermatitis is an inflammation of the skin caused by contact with certain plants during recreational or occupational exposure to sunlight. The inflammatory response is a phototoxic reaction to photosensitizing chemicals in several plant families; Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Chloroquine hyperpigmentation pictures face Melasma Chloasma - Pictures, Causes, Symptoms and Treatment., Skin Pigmentation with Hydroxychloroquine Plaquenil. Aralen reviewsDifference chloroquine bafilomycin a1Chloroquine trade name generic nameDifference between chloroquine and primaquine Hyperpigmentation is the production of excess melanin causing dark spots on the skin. Age spots, liver spots, freckles, sun spots, pregnancy mask are all types of hyperpigmentation and there are several treatments available to reduce or remove the darker skin. Hyperpigmentation Treatments, Causes & Photos - RealSelf. Allergic Skin Disorders - MedicineNet. Before/After Patient Photos Hyperpigmentation, Inflamed.. Generally, dark color skin people have more melanin than light color skin people. When melanin forms deposit in the skin it causes pigmentation. There are two types of pigmentation Hyperpigmentation, and Hypopigmentation. Hyperpigmentation is a normal and harmless condition in which the skin becomes darker in color than the normal surrounding. Mar 15, 2018 "Hyperpigmentation lasts longer in darker skin types because the more melanin that is produced, the deeper it sinks into the skin and the harder it is to get rid of," says Lily Talakoub, a. Addison's disease can affect the skin and cause hyperpigmentation. Pictured is the hand of a person suffering from Addison's associated hyperpigmentation alongside the hand of a person who does not have the condition, but who comes from a similar ethnic background. An accident or illness can worsen the skin hyperpigmentation of Addison's disease.