Note the presence of a confluent, erythematous eruption that is not only in a photodistribution but is now on the breasts and upper abdomen. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Can plaquenil cause numbness in tailbone area and legs Macrobid and hydroxy chloroquine interactions Side effects of Plaquenil and Azulfidine that are similar include nausea, vomiting, loss of appetite, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, or itching or skin rash. Side effects of Plaquenil that are different from Azulfidine include stomach pain or cramps, weight loss, mood changes, nervousness, irritability. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Skin conditions associated with lupus are fairly significant and a major marker of the disease. Of the eleven criteria set by the American College of Rheumatology for a diagnosis of lupus, four are skin-related. These include Malar rash - “butterfly rash” that appears on the cheeks; Discoid rash - red patches on the skin that can lead to. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil rash skin Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Hydroxychloroquine MedlinePlus Drug Information Chloroquine phosphate freshwater fish PLEASE HELP! I have been on Plaquenil well the generic form-- hydroxychloroquine since October, and for the past about 2 weeks, I have been SEVERELY skin turns red, and it feels like something is biting me. Plaquenil and SEVERELY ITCHY SKIN! PLZ HELPPP. - Inspire. Rashes, Skin Care and Cutaneous Lupus What You Should Know. Hydroxychloroquine Side Effects, Dosage, Uses, and More. What are the side effects of Plaquenil? The most common side effects are diarrhea, nausea, vomiting, headache, dizziness, skin rash or black spots when you look at things. Most side effects will go away when your body gets used to the medicine. So has anybody else had weird rashes like this. I hate to give up the Plaquenil because it has helped TREMENDOUSLY with the joint pain in my hands and hips. But i will try to get off it and see if this rash clears up. It itches so badly. And the skin on my hands feel tight-- like dried glue is stretching the skin, but it looks all wrinkly and. Plaquenil has beneficial effects on 3 major aspects of lupus; skin rashes, aches & pains and fatigue. It has also been found to help in a number of other features of the disease, though less predictably. It is very effective in the treatment of a whole variety of lupus skin rashes, particularly those found to be worsened by sunlight.