In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil and weight gain forum Can plaquenil cause hair loss Plaquenil effets secondaires peau Chloroquine during early pregnancy Hi Xtina333-I have sjogrens, was diagnosed with the positive ana and the ssa and ssb tests. I am taking plaquenil for joint pain and stiffness, fatigue, neuropathy and many other symptoms I will not even mention here, too many, too boring! I know you said that your initial tests for celiac disease were negative - are they going to biopsy your duodenum to be certain? I've never had diarrhea or weight loss from Plaquenil but clearly there are people who can't tolerate Plaquenil's side effects and can't take it. Hi Terri I'm really sorry you couldn't tolerate the Plaquenil. There have been others who have had the same problem. I believe some people have gone on to try another kind of anti-malarial, because that is what Plaquenil is - but I can't for the life of me think of the other names/names. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Sjogren's i can't tolerate plaquenil If you can't take Plaquenil DailyStrength, Plaquenil, diarrhea and weight loss? - Sjogren's World Plaquenil and flu shotMolecular weight of chloroquine phosphateAao plaquenil guidelinesPlaquenil 200 mg tablet nedirDrug warnings for plaquenil Then it went away, and I haven't had any side effects since. Like Lynnwood said, if the GI distress keeps up for ten or more days, let your doctor know. I've also heard that some people who can't tolerate the generic of plaquenil hydroxychloroquine because of the GI upset do okay on the brand name Plaquenil. Plaquenil -. Plaquenil - Sjogren's World. Hydroxychloroquine User Reviews for Sjogren's. -. Great question Anne! For some people, it may be diagnosed for another autoimmune disease. But it seems as though there is more recognition of Sjögren’s as being responsive to many of the same meds used for other autoimmune disorders. What I have noticed is that plaquenil seems to be diagnosed when there is ongoing fatigue and/or joint pain. I am only 30 and have only had these symptoms since October last year, so I am not at all sure this is Sjogren's. I'm going for a follow up with my rheumatologist on the 24th and he has said that I can go on a six month trial of Hydroxychloroquine Plaquenil if I want, but I am not sure if I should without a definitive diagnosis. I truely wonder if some people may have food allergies or intolerances that also increase their chances of having plaquenil upset their stomach? I know that I couldn't tolerate much until I went gluten free & stopped eating other foods that I found out I was allergic to but was consuming. I still can't tolerate a lot of different kinds of meds.