Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Sle hydroxychloroquine Plaquenil staggered dose Is uti a side effect of hydroxychloroquine When I was on plaquenil twice a day my dr has reduced it now says I was taking too much for my weight, really. I would take one in the morning with breakfast and one at night after supper. It bothers my stomach so I find it is best to take it with food. Hello friends, I take my Plaquenil in the morning with breakfast. I feel very shaky, dizzy and just off all day. Does anyone take it at night? Will it keep me up? Why do I have to take it in the morning. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. When is it best to take plaquenil Healthboards - Bone Joint Muscle - Arthritis best time to take, Can I take Plaquenil at night? - Sarcoidosis - Inspire Plaquenil side effects eyes symptoms Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Plaquenil Oral Interactions with Other Medication. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. What You Need to Know About Plaquenil. Plaquenil is a slow-acting drug. People who take Plaquenil may begin to notice improvement after one or two months. It may take up to six months before the full benefits of Plaquenil are realized. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. 5 The. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few months, but it can take up to six months for full effects. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. You may not see the best effect of this.