Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Can i take zyrtec with plaquenil Could you develop a rash 3 weeks after starting hydroxychloroquine Hydroxychloroquine sulphate overdose Jul 11, 2017 Porphyria cutanea tarda can increase the risk of liver cancer or cirrhosis, which is scarring of the liver. This is why it’s important not to drink alcohol if you have this condition. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. My oncologist will not allow me to add a targeted therapy or chemo while on this regimen and is very reluctant to prescribe chloroquine or a derivative to me. We settled on hydroxychloroquine which seems to work as well as chloroquine phosphate. I tried adding artemisinin and it seems to help although I can tell it is too hard on my liver. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Chloroquine and liver cancer Chloroquine - Memorial Sloan Kettering Cancer Center, Chloroquine - Wikipedia How long do hydroxychloroquine side effects lastHera study hydroxychloroquineMethotrexate and hydroxychloroquine Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating. Chloroquine Memorial Sloan Kettering Cancer Center. Chloroquine and Metformin - Empowering Cancer Patients to.. The Chloroquine Story in Cancer Continues In the Pipeline. Realizing that profuse activation of autophagy may contribute to pancreatic tumor growth, researchers designed an experiment in which they planned to treat the pancreatic cancer cell lines with Chloroquine, already known as inhibitor of autophagy. As a control, chloroquine was also used to treat normal cell lines with low expression of autophagy. Chloroquine inhibits NETs and diminishes hypercoagulability. These findings support clinical study of chloroquine to lower rates of venous thromboembolism in patients with cancer. Chloroquine CQ, the worldwide used anti-malarial drug, has recently being focused as a potential anti-cancer agent as well as a chemosensitizer when used in combination with anti-cancer drugs.