Hydroxychloroquine (Plaquenil) is an anti-malarial medication used for a variety of inflammatory diseases including systemic lupus erythematosus as well as rheumatoid arthritis and Sjogren's Syndrome. Hydroxychloroquine is contraindicated for Marshall Protocol Plaquenil lingers in the system at least 50 days and cannot be taken while on the MP. Blaney reports he starts his patients on Benicar while they are waiting for Plaquenil to clear their system and has seen no adverse events. Plaquenil and gabapentin Is plaquenil a blood thinner Plaquenil and wellbutrin Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. Have been on methotrexate 20mg firstname.lastname@example.org for about a year and 1/2. Recently moved and have a new Rheumatoligist who did his own blood test and x-rays, according to him he cannot find the blood factor or damage to any joints to prove that I have RA. I would like to know can I stop taking methotrexate or do I have to ween off of it slowly? Or should I even be thinking of stopping the meds? I. Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. I have been on the plaquenil 200 mgm for about 4 months now. He prefers to wait a couple months before starting minocycline. How to wean off plaquenil Stopping Plaquenil - General Discussion - Life With Lupus, Stopping Methotrexate - Arthritis Information Plaquenil hydroxychloroquine retinopathy Swallow the tablet whole. Do not crush, break, or chew it. Take this medicine with meals or milk to lessen stomach upset, unless otherwise directed by your doctor. Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Hydroxychloroquine MedlinePlus Drug Information. Can I stop my immunosuppressant abruptly or do I need to wean.. I have been taking Plaquenil 400 mg per day for about 2 years now due to lupus flare. When i first started it, I was also started on prednisone to get my inflammation under control. Actually I started on 200 mg per day and about 2 months before tapering off pred, he upped me to 400 mg per day of plaquenil to give it plenty of time to kick in. It's ok to stop plaquenil without weaning, but I do recommend that if you feel you can wait til Monday, wait, and talk with your rheumy then. I felt that plaquenil wasn't helping, and was causing digestive problems for me, so with my dr. ok, I went off it. After two weeks off, I discovered it had been doing some good on the joint and muscle pain. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues.