My rheumatologist is running tests but thinks I have a mixed connective tissue disease. I noticed plaquenil helping with my fatigue more so than anything else. I just want some relief from the knee, shoulder and wrist pain. It does help my joint pain but I need extra help from other meds too It can take up to 6 months to get in your system and fully work, each person is different. Side effects of quitting plaquenil Ocular side effects from plaquenil How to pronounce chloroquine Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. A product containing 5-Loxin and Salicin white willow bark helped my daughter with her joint pain enough that she was able to stop using Voltaren Gel. Salicin is a mild NSAID, which is a prostaglandin inhibitor. 5-Loxin is a leukotriene inhibitor. Both are OTC. NSAIDs alone didn't help my daughter, but adding 5-Loxin was a game changer for her. Jan 11, 2020 Yes, plaquenil does decrease my joint pain dramatically. January 12, 2020 at pm I’ve been on plaquenil for almost 4 years with no side affects. It has helped some with my joint pain and fatigue. If it does not help the joint pain be sure to talk to your doctor, there are other meds they can give you to help. From what I understand, it is "the first line of defense" and definitely worth a try! I pray it doesn't take that long for you to get some relief. Plaquenil was great for the pain and swelling but did almost nothing for the fatigue. Of all the meds, Plaquenil was the best for me and helped the most, but some people don't tolerate it. Plaquenil helps joint pain Joint Pain and Plaquenil Sjogrens - reddit, Does Plaquenil help with Joint Pain? - Autoimmune diseases. Allergic reaction when changed from hydroxychloroquine to plaquenilMalaria hypnozoites resistant to chloroquine Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Lupus Medicines Hydroxychloroquine - Brigham and Women's Hospital. Does Plaquenil help joint pain? - Autoimmune diseases - Inspire. Osteoarthritis - Diagnosis and treatment - Mayo Clinic. Hello, I thought fatigue is one of the symptoms of RA, so taking the right medication should help lessen fatigue, shouldn't it? When I was diagnosed with RA 2.5 years ago, I experienced fatigue and really bad pain on my foot, but since I started Plaquenil and Orencia 2 years ago, I have been in medically induced remission and don't have fatigue anymore. According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with arthritis. It can also reduce the incidence of joint damage, thus lessening the risk of developing a long-term disability from. Check the latest outcomes from 53,829 Plaquenil users, or browse all drugs. What is Osteoarthritis? Osteoarthritis a joint disease caused by cartilage loss in a joint has been reported by people with osteoporosis, rheumatoid arthritis, high blood pressure, osteopenia, pain.