I can say that I am not having pain like I used to, and I am so grateful for that! I don't know if this is just the RA in full swing, or if it is a side effect of the Plaquenil. I have been running a low-grade fever (around 99.8) for about a week and a half now. Hydroxychloroquine sweating Chloroquine phosphate 500 mg dosage Stomach digestion meditcation plaquenil Hydroxychloroquine is the immunomodulatory drug most frequently used for primary Sjögren syndrome, 7 usually prescribed for patients with fatigue, arthralgia, and myalgia 8-10 rather than severe systemic manifestations. The latter symptoms are treated with corticosteroids and azathioprine, cyclophosphamide, mycophenolate mofetil, or rituximab. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Fatigue is so frustrating for patients, but we don’t know much about it,” says Maria Dall’Era, MD, director of the Lupus Clinic and Rheumatology Clinical Research Center at the University. My normal body temperature is low, around 97.5, so I don't know if 99.8 would be considered a fever. It comes & goes and I can tell when it is up because I feel hot. Plaquenil et fatigue Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Clinical pharmacology of chloroquin With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Lupus Fatigue Causes and Treatment Tips. Is extreme fatigue a side effect of Plaquenil - NRAS. Jun 21, 2015 Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Fatigue is a very common complaint among those living with lupus. HSS Rheumatologist, Dr. Jessica Berman indicates that research estimates 40% of lupus patients have persistent severe fatigue, meaning that the fatigue stays for a long period of time.